Skin Cancer

Skin Cancer represents the most common form of malignancy worldwide, encompassing melanoma, basal cell carcinoma, squamous cell carcinoma, and rarer cutaneous tumors. Despite its prevalence, early detection and timely intervention dramatically improve survival and functional outcomes. As a cornerstone topic at every international Dermatology Conference, this session provides a comprehensive exploration of epidemiology, screening strategies, diagnostic precision, and therapeutic innovation. Closely aligned with cutaneous oncology management, skin cancer care requires a balance between oncologic safety, tissue preservation, and long-term surveillance.

The session begins with a review of ultraviolet radiation–induced DNA damage and the molecular mutations that initiate carcinogenesis. Chronic sun exposure, immunosuppression, genetic predisposition, and fair skin phenotype remain significant risk factors. Participants will examine how cumulative UV exposure leads to keratinocyte mutation and melanocyte transformation.

Clinical recognition remains critical. Suspicious pigmented lesions, non-healing ulcers, evolving nodules, and persistent scaly plaques demand thorough evaluation. Dermoscopy enhances early identification by revealing vascular patterns, pigment networks, and structural asymmetry. Biopsy techniques provide definitive diagnosis and guide staging.

Treatment modalities vary depending on tumor type and stage. Surgical excision remains the primary approach for most localized cancers, while Mohs micrographic surgery offers superior margin control for high-risk lesions. For advanced disease, targeted therapies and immune checkpoint inhibitors have revolutionized management, particularly in melanoma and aggressive squamous cell carcinoma.

Non-invasive therapies, including topical chemotherapeutic agents and photodynamic therapy, are appropriate for selected superficial tumors. Preventive strategies such as sun protection education, routine screening, and monitoring of high-risk patients are emphasized to reduce long-term disease burden.

The session also highlights survivorship care and recurrence monitoring. Patients with a history of skin cancer face increased risk of subsequent lesions, necessitating structured follow-up protocols.

By integrating prevention, early detection, surgical precision, and systemic therapy innovation, this session equips dermatologists with a comprehensive framework for managing skin cancer across diverse clinical presentations.